Replicative aging of Saccharomyces cerevisiae is an established model system for eukaryotic cellular aging. A limitation in yeast lifespan studies has been the difficulty of separating old cells from young cells in large quantities. We engineered a new platform. the Miniature-chemostat Aging Device (MAD). https://www.parisnaturalfoodes.shop/product-category/kids-toothgel/