Keratinocytes are the first cells that come into direct contact with external tactile stimuli; however. their role in touch transduction in vivo is not clear. The ion channel Transient Receptor Potential Ankyrin 1 (TRPA1) is essential for some mechanically-gated currents in sensory neurons. amplifies mechanical responses after inflammation. https://www.findingthestory.com/product-category/metal-cored-wire/